The actress can be seen starring opposite the action star in comedy sequel Housefull 2.
She told The Times of India: "Akshay Kumar is the sexiest actor I have worked with. Shooting with him is loads of fun because he keeps you on your toes all the time.
"I love his straight-faced sense of humour. He acts so innocent that you really don't expect him to play any prank on you. He is a prankster.
"You have to be really careful about your phone when he is around, he'll just whisk it away and do crazy stuff.
"Akshay is an early morning person and so am I. He is a very disciplined and professional actor. He has a particular time to go to bed. He gets up early in the morning and reports to work on time.
"He wraps up on time. There's much to learn from him."
In January, it was reported that Thottumkal snubbed former boyfriend Neil Nitin Mukesh at a social function.
She recently admitted that she bitches about the film industry with other female Bollywood stars.