The show's bosses reportedly attempted to secure the 'Someone Like You' singer for the Judges' Houses round of the competition, but prior work commitments did not allow for her participation.
A source told the Daily Star Sunday that Cowell is aiming to recruit Adele to perform on both the UK and US versions of the show following an incredibly successful year on both sides of the Atlantic.
"There's no denying Adele is the biggest singer in the world right now and Simon wants her to appear on both the UK and US X Factors," the insider said.
"He couldn't get her for the Judges' Houses stage, so he now wants her to sing with one of the contestants on the grand final in December.
"She is a massive fan of the show and even went to watch the US X Factor auditions earlier this year."
The new panel of judges - consisting of Gary Barlow, Louis Walsh, Tulisa Contostavlos and Kelly Rowland - had urged hopefuls to avoid singing Adele cover versions at auditions earlier this year.
Adele's 21 album was recently certified triple platinum after it managed to shift approximately three million copies in the US.
Watch Gary Barlow, Tulisa Contostavlos, Kelly Rowland and Louis Walsh in the first X Factor trailer below: