The former Emmerdale actress has been linked to the show in a number of press reports. If confirmed, she would appear alongside Matt Smith's Time Lord in the BBC sci-fi's seventh series, replacing Karen Gillan (Amy Pond) and Arthur Darvill (Rory Williams).
An official announcement is expected later today (March 21), with a message on the official Doctor Who Twitter feed stating: "Good morning! A few announcements coming your way this morning. That's right - a few!"
Jenna-Louise Coleman in 'Titanic' (left) and BBC One's 'Waterloo Road' (right)
Coleman, who was born in Blackpool, landed the part of Jasmine Thomas in Emmerdale in 2005, and has also appeared in Waterloo Road and Captain America: The First Avenger.
The 25-year-old will soon be seen as cabin steward Annie Desmond in Julian Fellowes's drama Titanic, commissioned to mark the centenary of the ship's sinking.
Gillan was confirmed to be departing Doctor Who along with co-star and on-screen husband Darvill back in December.
It is known that they will leave part way through series seven in a "heartbreaking end", and Gillan has teased that her exit will have a "strong impact".
She also assured fans that her final Doctor Who storyline is "going to be damn good", adding that Amy will go out "on a high".
Watch Karen Gillan discuss her Doctor Who exit below:
> Doctor Who's Karen Gillan: 'Exit will be strange shock to the system'
See a gallery of previous Doctor Who companions below: