The book was released as part of the publisher's Political Power series, which has previously focused on Barack Obama, George W. Bush and Joe Biden.
"I think the crux of the book will be the assessment of whether Reagan was simply at the right place and time when the Soviet Union fell," said author Don Smith. "Or was he one of the shrewdest occupants of the White House?"
Drawn by Heath Foley, the one-shot examines Reagan's career as a B-movie actor, his time in politics and his battle with Alzheimer's disease. Bluewater will follow the issue with a comic dedicated to conservative pundit and radio show host Rush Limbaugh.
Political Power: Ronald Reagan is available in stores now.