Chris Ryall - the publisher's Eisner Award-winning chief creative officer - will attend the event in February.
IDW will be reviewing portfolios at the comic convention in the hope of signing some new talent.
The convention will also mark the first appearance of Stan Lee in the UK for almost 40 years.
Other guests at the event include Brian Bolland, Mark Buckingham, Howard Chaykin, Ian Churchill, Mike Deodato Jr, Jamal Igle, Phil Jimenez, Andy Lanning, Tony Moore, George Perez, Bill Sienkiewicz, Fred Van Lente and Bernie Wrightson.
The inaugural London Super Comic Convention will be held at London's ExCel centre on February 25 and 26.
The London-based Kapow! Comic Con will also be celebrating its second year in the capital in 2012.