The ongoing series, written and illustrated by Dan Parent, sees the publisher's first openly gay character take centre stage.
Keller was introduced in a 2010 issue of Veronica, and starred in his own miniseries the following year. The character was married off in last month's Life with Archie #16.
"Even though it's been a fast rise for him, he's brought in a lot of new fans because of the publicity he's gotten," Parent told Newsarama.
"They seem to be sticking around. First, we attracted a lot of the readers because of the novelty that we never had a gay character, but the people are turning out for the Kevin books, so it appears that he has a loyal following."
Other Archie characters to be given solo titles include Archie, Jughead, Betty and Veronica.
Kevin Keller #1 is available in stores now.