The classic arcade game allows up to four players to control Homer, Marge, Bart and Lisa as they fight through Springfield past Mr Burns's goons.
Konami is updating the game with online co-operative play, bonus modes, an option to play the modified Japanese version and support for achievements and trophies.
The Xbox Live Arcade version will release first, arriving this Friday, February 3 for 800 MS Points (£6.80 / $10).
On PlayStation 3 the game comes out February 7 in North America and February 8 in Europe for $9.99 and £7.99 respectively.
PlayStation Plus subscribers will also be able to download the game for free during the month of February.
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Watch footage of The Simpsons Arcade below: