Lead designer Hayden Dalton has said that the action-adventure sequel will be available "day one" on Nintendo's new console when it launches.
It is currently being developed alongside the other console versions, with a small team dedicated to ensuring it uses the controller in "a unique way".
"That's been very interesting to see what those guys are doing, and they're making efforts to make sure we do use it in more than a slapdash way," he told Digital Spy.
"It's basically the core game, but then with added abilities to do certain things that you can't do on the other consoles."
While Dalton couldn't give specific examples, when the Wii U version was originally going to be shown it featured the ability to change equipment on the fly.
"One of the things that we did, when we were originally going to show it off, was that you could equip stuff directly. So, for instance, I could be running along and I could click on another piece and I could put it on as I'm running through the game," he revealed.
"That's huge, it's not breaking up the game in a way, I'm not going into a menu and assigning it, I'm literally just tapping as I'm playing."
He continued: "We're not basically heavily changing the core game to support the control system, but the control system will be an enhancement of the core game."
Darksiders II will be available from June 26 in North America and June 29 in the UK for Xbox 360, PS3 and PC.
> Read our preview of Darksiders II
> Read our Darksiders II interview with Vigil Games
Watch a trailer for Darksiders II below: