Little is known about the game, with its developers only referring to it as a "new AAA RPG".
The teaser image reveals a futuristic cyberpunk setting, with a mohawk-adorned character holding a pistol and wearing augmented reality glasses.
The new game will be announced during CD Projekt's pre-E3 Summer Conference tomorrow.
Rumors have also suggested that the studio will announce PlayStation 3 and Xbox 360 ports of The Witcher during tomorrow's Summer Conference.
The Witcher 2: Enhanced Edition, meanwhile, launched on the Xbox 360 last month.
The game features a new opening cinematic, additional characters, new missions and locations.
The Xbox 360 release also contains a new user interface, as well as all of the DLC previously offered for free to PC users.
> The Witcher 2: Enhanced Edition review: An engaging fantasy epic
Watch a trailer for The Witcher 2: Enhanced Edition below: