Series creator Shigeru Miyamoto told Entertainment Weekly that they are currently experimenting with the game's control scheme.
He said: "With the last game, Skyward Sword, that was a game where you had motion control to use your weapons and a lot of different items, and I thought that was a lot of fun.
"But there were some people who weren't able to do that or didn't like it as much and stopped playing partway through it."
Nintendo showcased a Legend of Zelda-themed tech demo at E3 2011, but there were no announcements about the game at this year's event.
> E3 2012: All you need to know - pictures
Miyamoto went on to say that the next entry in the series will be accessible to a wide audience.
"We're seeing how the way that tastes are broadening in video games and you have some people who prefer more casual experiences, and you have some people who prefer sort of those more in-depth experiences," he added.
"Obviously, as a company that's been making games for a very long time, we tend to be more on the deeper, longer game side of things.
"But really what we continue to ask ourselves as we have over the years is, 'What is the most important element of Zelda if we were to try to make a Zelda game that a lot of people can play?"
Nintendo is yet to announce a specific release date for the Wii U, though recent reports suggest a November launch.
Watch a video introducing the Wii U GamePad below: