The CG trailer, which aired in full during last week's Ubisoft E3 2012 press conference, shows Sam Fisher using all-new gadgets to rescue a hostage.
Meanwhile, the title has also been listed for Wii U on US shopping site Best Buy.
Splinter Cell: Blacklist was unveiled during Microsoft's E3 press conference.
The game will feature Kinect integration, allowing players to distract enemies and call for support using voice commands.
A new Splinter Cell has been rumoured since the release of Conviction in 2010.
The game was outed in a promotional video by Ubisoft's Jade Redmond, who confirmed that the game would be developed entirely in Toronto.
Splinter Cell: Blacklist is currently confirmed for the Xbox 360, PS3 and PC. It releases during the early stages of 2013.
Watch a gameplay demo for Splinter Cell: Blacklist below: