Ridley Scott directed the 1982 film which starred Harrison Ford as detective Rick Deckard, who was forced to hunt down four escaped human replicants in Los Angeles circa 2019.
The picture also featured Rutger Hauer, Sean Young and Daryl Hannah, and was based upon the novel Do Androids Dream Of Electric Sheep? by Philip K. Dick.
The adaptation bested such genre favourites as Star Wars, 2001: A Space Odyssey and Alien to place first in The 100 Greatest Sci-Fi Movies list on Total Sci-Fi.
It was reported last year that Eagle Eye screenwriter Travis Wright was penning a follow-up to the sci-fi classic.
Scott recently confirmed that he will direct a prequel to his 1979 film Alien, which starred Sigourney Weaver.