The actress told The Times that her co-stars helped her to develop her acting skills.
"I felt like it was acting school, working with all these people," she said. "They make really brave choices. They showed me that, as an actor, you have to be prepared to do things that you could completely mess up, or that people may not like. But it's much more interesting playing a character that's not instantly likeable."
Wasikowska described her co-star Johnny Depp as "nice and kind and just an incredible actor" and explained that he and director Tim Burton have their own "language".
"On the set, they have this push-pull thing," she said. "They keep each other in check, but they can also just say one thing to the other and know exactly what they mean."
However, Wasikowska admitted that she found it difficult to work with a green-screen instead of other actors.
"When you're acting with a tennis ball that is supposed to be the Cheshire Cat, you don't know what the Cheshire Cat is giving you, so you're having to pretend you know," she explained. "It really meant a leap of faith, and having to trust Tim when he says things like, 'Be a bit more angry with it'. But it's hard, because you're really filming in a void."
Wasikowska added that watching the finished movie was "fascinating" but explained that she doesn't like seeing herself on screen.
"It's painful," she said. "A kind of traumatic experience, thinking, 'Oh, I should have done this or that differently'."
Alice In Wonderland opens in cinemas on March 5.