The Avengers actor told Digital Spy that the mythology for the character gives producers the opportunity to make up to six films if fans want to see them.
"We're responding to what people make of it, there's such a depth of layering in comics to his character," he said at last night's (March 25) Empire Awards.
"Loki goes on forever, it's a mythology, it goes deep. If we were allowed to make six films we could, we'll just have to see."
Talking about rivalry with his fellow castmates, Hiddleston added: "I'm pleased to say all our trailers were [the] same size. Chris Hemsworth's biceps are bigger than everybody else's, that was enough."
Captain America (Chris Evans), Iron Man (Robert Downey Jr) and Thor (Chris Hemsworth) lead The Avengers in the superhero project, with Hulk (Mark Ruffalo), Hawkeye (Jeremy Renner) and Black Widow (Scarlett Johansson) joining the fight to save the world.
The Avengers opens in UK cinemas on April 26 (under the title Marvel Avengers Assemble) and on May 4 in the US.
Additional reporting by Simon Reynolds
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