The pair star as former enemies who are forced to live together, and later decide to set up their own sex hotline in order to make money.
Through their unexpected success, a friendship is formed between the pair.
Watch the trailer below (NSFW):
Miller's real-life husband Seth Rogen and Justin Long also feature in the film from first-time director Jamie Travis.
It debuted at the Sundance Film Festival earlier this year, and will be released in the US on August 31. There is currently no release date set for the UK.
Miller married Rogen in October last year.