The Emmy nominee will join Ron Perlman, Titus Welliver, Ron Eldard and Beau Mirchoff in the Greg Francis-directed indie thriller, reports Deadline.
The film centres around a young cop who is being tracked by a serial killer.
During regular poker games he plays with police veterans, he hears stories that hold the clues he needs to ensure his survival.
Esposito will play one of his fellow poker players, Detective AJ Bernard.
The actor is best known for his roles in Breaking Bad and NBC's Revolution.