Scooter Braun, who is Bieber's manager, has revealed that the 18-year-old is a fan of the X Factor group and that a collaboration between them is "very possible".
During a live question-and-answer session on Twitter, a fan asked Braun: "Do you think Justin could ever possibly collab with One Direction?"
He replied: "Very possible. He likes them and thinks they are good dudes. All people of that generation should be there to help each other."
Bieber is preparing to release his third studio album Believe and will debut his new single 'Boyfriend' on March 26.
Meanwhile, One Direction are currently touring the US with Big Time Rush and recently allegedly got told off by record label bosses after trashing a bowling alley in New York during a post-gig party.
Listen to Justin Bieber's recent collaboration with Far*East Movement called 'Live My Life' below: