The 'My Heart Will Go On' diva sang Adele's 'Rolling in the Deep' during a performance at Caesar's Palace in Las Vegas, where she has a permanent show.
Before performing a faithful cover of the 21 star's track, Dion told the cheering crowd: "I love Adele so much, she's amazing!"
The singer recently recovered from vocal chord surgery she had done in March, similar to a surgery Adele received last year after her own throat problems.
Adele's album 21 won six Grammys this year, including 'Song of the Year' for 'Rolling in the Deep'.
The album recently dropped out of the top ten on the UK album charts for the first time since its release in January 2011.
Listen to Celine Dion's cover of 'Rolling in the Deep' below: