Power was cut two songs after Paul McCartney joined the singer-songwriter and his E-Street Band's Hyde Park set as the show ran beyond its curfew.
"As a longstanding Bruce Springsteen fan and one of the crowd at Hard Rock Calling, I was doubly disappointed to hear Live Nation give 'health and safety' as the reason for cutting short Saturday's gig," said HSE deputy chief executive Kevin Myers in a statement.
"The fans deserve the truth: there are no health and safety issues involved here. While public events may have licensing conditions dictating when they should end, this is not health and safety and it is disingenuous of Live Nation to say so."
He added: "It's ironic that this excuse has been used in relation to Bruce Springsteen, who certainly knows what real health and safety is all about - look at the words of 'Factory' from Darkness on the Edge of Town referring to the toll that factory work can take on the health of blue collar workers.
"People will now only be able to speculate what the final number should have been. Given that he'd already played 'Wrecking Ball' and that Paul McCartney was on stage, how about 'Don't Let Me Down'?"
Photo gallery - Hard Rock Calling 2012
Copyright: PA Images Lewis Whyld/PA Wire