Muse debut new single 'Madness' - listen
The track will be available to download later tonight (August 20) after it premieres on BBC Radio 1.
'Madness' is the second song to be taken from the band's new album The 2nd Law, following the release of the official Olympics single 'Survival'.
The 2nd Law was originally due to be released on September 17, but Muse have pushed the date back to October 1.
"Every time you finish a new album you feel excited and nervous and anxious about what's going to happen with it when it gets released, but with this one we've discovered some new ideas for our band," drummer Dominic Howard told NME.
"Every album for me seems to open up doors to the future and this one does more than ever."
Muse recently unveiled the full tracklisting for The 2nd Law and announced a UK headline tour for October.