The 'Edge Of Glory' singer was joined by her mother Cynthia Germanotta, president of the organisation, Oprah Winfrey and guru Deepak Chopra at a gala in Harvard University's Sanders Theatre yesterday (February 29).
Speaking to a panel of over 1,100 students and faculty members, GaGa explained that the foundation was designed to "challenge meanness and cruelty by inspiring young people to create a support system in their respective communities".
"If you have revolutionary potential, you must make the world a better place and use it," she said, adding later: "When I say it takes very little to change the world, I really mean that.
"If each one of us just transformed one small bit of ourselves to be a bit kinder, more loving, more tolerant... I believe it will be quite easy to change the world."
GaGa also announced that a 'Born Brave Bus', where fans can gather to talk about their issues, will travel to dates on her upcoming 'Born This Way Ball' world tour.
> Lady GaGa: 'Bullying stays with you for life'
Watch Lady GaGa in the video for 'Born This Way' below: