The couple, who wed last July in a Cotswolds village, are reportedly planning a party for friends, as well as getting tickets to attend the music event.
A source told The Sun that the supermodel is working hard to spend time with the Kills guitarist.
They revealed: "Kate is going to spend some time with Jamie on the Kills' tour next month.
"After that, they're going to try to squeeze in a holiday to Sri Lanka for some time alone together. Then a group of their friends are joining them on the Isle of Wight for a proper boozy wedding renewal celebration."
According to the insider, Moss is "keen to show everyone that just because she's married, it doesn't mean she's going to slow down any time soon".
Last year, the 38-year-old fashion icon spent time at the festival with 12 friends, including The Kills singer Alison Mosshart, Jade Jagger and Sadie Frost.
The Isle of Wight Festival takes place between June 21 and June 24 at Seaclode Park, Newport.
Acts confirmed for this year's event include Lana Del Rey, Noel Gallagher's High Flying Birds, Elbow, Labrinth, Enter Shikari and Kelis.
> Kate Moss, Kristen Stewart planning duet