The actress announced the new relationship on Chicago's NBC 5 during an autism charity event, according to People.
"I can confirm that yes it's true, we are dating," she said.
McCarthy and Urlacher have been spotted together in Chicago. According to a rep for McCarthy, they have been dating for about a month.
The 39-year-old rose to fame in the '90s on MTV's Singled Out. She dated actor Jim Carrey for five years until their split in 2010.
McCarthy will next be featured in a photoshoot for Playboy magazine.
She tweeted recently: "Why should only 20 yr olds be considered sexy? Let's [hear] it for the MILFs."