The former Office actor stars alongside Tatum in the upcoming film Foxcatcher, which tells the true story of a millionaire who built a wrestling training site only to murder gold medalist David Schultz.
"I'm excited," Carell told MTV News. "It's a good script."
He went on to say that he is not intimidated by Tatum's famous abs.
"We could have a pose-off right now, and I would just win hands down - no competition there," Carell added.
"He doesn't threaten me. Come on!"
Foxcatcher, which is being directed by Bennett Miller, also stars The Avengers' Mark Ruffalo. It is due to begin filming in October.
Watch Channing Tatum in the red band trailer for Magic Mike below: