The Hollywood actor posed for a couple of photos with a fan in a restaurant, with the young man pretending to be drunk and slumped on his shoulder.
The fan also appears face down in his pizza, while Hanks looks on confused.
Hanks plays along with the gag, laughing and pointing as the man pretends to be asleep on his shoulder, having taken the star's glasses.
The photos have been viewed over four million times since they were uploaded to Imgur earlier this week.
A post on Reddit linking to the photos read: "My friend met Tom Hanks, stole his glasses and pretended to be wasted."
It is currently unclear who the fan is, or where the photo was taken, but Hanks has recently been on vacation in Fargo, North Dakota, with his wife Rita Wilson.
Tom Hanks recently announced plans to produce a new film about the assassination of John F Kennedy.
The actor will next be seen opposite Halle Berry in Cloud Atlas, to be released on October 26.
Watch the trailer below: