Last week, the nominees for this year's Billboard Music Awards were announced, with songstress Adele leading the competition with 18 nominations, followed by LMFAO with 17 nominations and Talk That Talk singer Rihanna with 13 nominations.
Bowen and Burrell can be seen playing married couple Phil and Claire Dunphy in ABC's Modern Family.
CEO Prometheus Global Media Richard D Beckman said: "We are thrilled to have television's favourite Emmy Award-winning couple as our hosts for this year's Billboard Music Awards.
"Ty and Julie have captured the hearts of America with their on-screen chemistry and humour - and we look forward to having them bring that magic to the Billboard Music Awards."
The 2012 Billboard Music Awards will air live from Las Vegas on Sunday, May 20 at 8pm ET on ABC.
Watch a video clip of Julie Bowen and Ty Burrell in Modern Family below (US only):