The Showtime thriller, which aired in the UK on Channel 4, will battle it out with Breaking Bad, Game of Thrones, Downton Abbey, Mad Men and Boardwalk Empire for the award at the September 23 ceremony.
In our poll, voted for by thousands of our readers, Homeland's first season came out on top with 30.9% of the vote.
The second season of Game of Thrones came second with 25.5% of the vote, while UK entry Downton Abbey has 20% of the vote.
Breaking Bad pulled 14.4% of the vote, ahead of the recent series of Mad Men with 6.7% and the second run of HBO's Boardwalk Empire with just 2.5%.
Jimmy Kimmel is hosting this year's Primetime Emmy Awards, which will be broadcast on ABC.