Mitchell, best known to viewers as Dr Juliet Burke from Abrams's hugely successful Lost, has signed on as a series regular for the new sci-fi series, which was recently greenlit by the network.
According to The Hollywood Reporter, Revolution is set in a world where every piece of technology, including cars, computers, phones and lights, has suddenly stopped working forever. The show follows a family as they attempt to reunite and navigate their way through this post-apocalyptic dystopia.
Mitchell will play Rachel Matheson, a terrified mother of two children. She takes over the role from Andrea Roth, who played Rachel in the original pilot.
Revolution will also feature Twilight's Billy Burke and Breaking Bad's Giancarlo Esposito in key roles, and will be directed by Iron Man helmer Jon Favreau.
This will mark Mitchell's first recurring role in a television series since ABC's V reboot was cancelled in 2011, after playing Juliet on Lost for four seasons.
Watch the trailer for Revolution below: