The show has used the trick before as it skipped forward four years between the fourth and fifth seasons.
Nichols has now told TV Guide that the drama will fast-forward again, although it will happen in the season finale instead of during the hiatus.
He said: "There is a really cool device in the finale... where we're jumping through months."
It is not yet clear whether One Tree Hill will be renewed for another season but Nichols suggested that the finale will be a suitable ending if the show does not come back.
"If it [is] in fact a series finale, it will be very satisfying," he said. "[But] I know that there are seeds planted if there's going to be another season. Everybody feels lucky to be a part of something that's been on so long, so we'll see."
One Tree Hill's executive producer Mark Schwahn recently confirmed that former cast members Chad Michael Murray and Hilarie Burton will not be returning to the show.
The series airs on Tuesdays at 8/7c on The CW.