It was previously reported that Battlestar Galactica actor Olmos will play a "brilliant" and "charismatic" professor of religious studies in the new run.
Lee, who plays Masuka on the Showtime drama, told TV Line that the character will likely serve as a new nemesis for Dexter (Michael C. Hall).
"It seems to be that way," he suggested. "The guy is such a wonderful actor and such a presence that you would probably shoot yourself in the foot if you didn't do that. He's going to be great."
Lee also revealed that forensics investigator Masuka will recruit a team of lab technicians to assist him with his latest case.
"I have a few 'lab helpers' coming in this year," he confirmed. "They're either going to help me or they're going to get me in trouble. We'll see what happens."
Colin Hanks, Brea Grant, Billy Brown, Mos Def and Molly Parker will all appear in the new season of Dexter.
> Dexter: Julia Stiles chats season five
Watch a teaser for the sixth season of Dexter below: